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Resveratrol
SupplementsEffort · LowEasy

Resveratrol

The red-wine polyphenol that activates longevity genes

1.1k
3.5(2)
1,280 upvotes · 145 downvotes

500mg of trans-resveratrol taken with a fat-containing meal for absorption. Resveratrol activates SIRT1 (a longevity sirtuin), mimics aspects of caloric restriction at the cellular level, reduces inflammatory cytokines that drive skin aging, and has shown measurable anti-aging effects on skin elasticity in clinical trials. Most effective when combined with NMN as part of a NAD+ optimization protocol.

Reviews

What the community says

2 verified voices, averaging 3.5 of 5.

L
Lara
May 23, 2026

Combined with NMN. Skin looks more radiant and energy is consistently higher.

0
G
Gio
Jun 22, 2026

Hard to isolate effects but I'm convinced it's contributing to my skin improving at 40.

0