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GHK-Cu (Copper Peptide)
SkinEffort · LowEasy

GHK-Cu (Copper Peptide)

Collagen, hair, and wound healing at the cellular level

1.6k
4.5(2)
1,760 upvotes · 195 downvotes

Glycyl-L-histidyl-L-lysine copper (GHK-Cu) administered topically at 1–2%, or via subcutaneous injection at 1–2mg per session. GHK-Cu is a naturally occurring human plasma peptide that declines with age — it stimulates collagen and glycosaminoglycan synthesis, promotes nerve regeneration, exerts powerful antioxidant effects, and has been shown in studies to reverse gene expression patterns associated with aging. Applied to the scalp, it activates hair follicle stem cells and has outperformed minoxidil in some models. One of the few peptides with substantial peer-reviewed evidence for both skin and hair applications. Available OTC as a topical; injectable form is a research chemical.

Reviews

What the community says

2 verified voices, averaging 4.5 of 5.

V
Vera
May 18, 2026

Added GHK-Cu topical to my scalp routine alongside minoxidil. Hair density improvement was faster than minoxidil alone. The collagen effect on facial skin is also visible.

0
N
Nora
Jun 22, 2026

Using the topical form on my face. Skin looks visibly thicker and more radiant after 8 weeks. The science on this one is actually solid.

0